Amala Institute of Medical Sciences (AIMS), Thrissur, actively promotes a multidisciplinary research culture that supports innovation in healthcare and medical science. As a leading medical college hospital in Thrissur, AIMS focuses on discovering, evaluating, and developing effective therapeutic solutions for a plethora of different diseases.

Research initiatives at Amala integrate basic science research, clinical research, and traditional medicine studies, with emphasis on cancer research, immunology, biochemistry, drug development, and integrative medicine. These activities of scientific enquiry directly contribute to improved patient care and medical education.

One of the major focus areas at Amala is cancer research, including studies oriented toward improving diagnosis, treatment, prevention, and quality of life for patients.
Key research domains include:

• Cancer- Biochemistry
  
• Cancer - Immunology
  
• Development of anti-metastatic drugs
  
• Chemoprevention and chemopreventive agents against cancer
  
• Radioprotective and radiosensitizing agents
  
• Drugs that inhibit oncogenesis and cancer growth
  
• Studies on lifestyle habits and cancer causation
• Palliative cancer therapy, including integration with modern treatment approaches

Active engagement in therapeutic research focused on discovering and developing novel drug candidates.
Ongoing research areas include:

• Development of plant-based and synthetic chemotherapeutic agents
  
• Antidiabetic drugs derived from plants
  
• Drug development for atherosclerosis
  
• Research on drugs targeting AIDS and related conditions
  
• Identification of antiviral and anticancer agents from fungi and mushrooms
  
• Development of callus cultures for the identification of anticancer drugs

Amala’s scientific programmes majorly include research in immunology and cardiovascular health.
Key areas of investigation include:

• Immunomodulators and their use in cancer therapy
  
• Biochemical and immunological investigation on the causes of coronary artery diseases
  
• Research on angiogenesis and immunomodulatory functions

Research on environmental and lifestyle-related health risks is also conducted at Amala. These studies aim to understand disease causation and prevention strategies, including:

• Impact of industrial pollutants on cancer development
  
• Relationship between lifestyle habits and chronic diseases

Amala undertakes extensive research in Ayurveda and integrative medicine.

• Standardization of herbal formulations
  
• Evaluation of Ayurvedic drugs as adjuvants in cancer therapy
  
• Clinical assessment of alternative systems such as Ayurveda and Homoeopathy in cancer care
  
• Development and evaluation of Ayurvedic herbal preparations against HIV/AIDS
  
• Exploration of affordable and effective Ayurvedic treatments for:
  

1. Rheumatoid arthritis
2.  Low back pain
3. Sciatic nerve disorders
4. Disc prolapses
5. Diabetes and other chronic conditions    

The research centre at Amala Institute of Medical Sciences has recorded several significant achievements, including the development of experimental models for:

• Transplanted tumours
• Chemically induced tumours
• Metastatic tumours
• Angiogenesis
• Immunomodulatory functions

Amala institute of Medical Sciences has always remained dedicated to advancing medical knowledge and contributing meaningfully to society at large. Our research activities aid improved healthcare, strong education for the future, and innovation at the medical level.